恭喜李国兴博士的研究成果被Chemical Science接受！

恭喜李国兴博士的研究成果被Chemical Science接受！

https://pubs.rsc.org/en/content/articlelanding/2019/sc/c8sc04134b#!divAbstract

Abstract

We report an efficient and economical method for remote δ C(sp3)-H heteroarylation of free aliphatic alcohols using hypervalent iodine PFBI-OH oxidant under photoredox catalysis. The reaction sequence features in situ alcoholysis of PFBI-OH with alcohol, generation of alkoxy radical intermediate by SET reduction, 1,5-HAT, and Minisci-type C-C bond formation. This method uses slight excess of alcohols, can react at δ methyl and methylene positions, and has been successfully applied to modification of complex drug molecules.