Gong Chen Lab @ Nankai / 南开大学陈弓课题组
Prof. Gong Chen (陈弓)
E-mail: gongchen@nankai.edu.cn
Education
1998 BS, Nanjing University, China 2004 PhD, Columbia University, USA
Academic career
2023-present Hongqin Endowered Professor of Chemistry, State Key Laboratory of Elemento-organic Chemistry, Nankai University, China
2015-present Professor, State Key Laboratory of Elemento-organic Chemistry, Nankai University, China
2018-2021 Adjunct professor, The Pennsylvania State University, USA
2014-2015 Associate Professor, Department of Chemistry, The Pennsylvania State University, USA
2008-2014 Assistant Professor, Department of Chemistry, The Pennsylvania State University, USA
2005-2008 Postdoctoral fellow, Memorial Sloan-Kettering Cancer Center, USA
Honors
ACP lectureship awards in Japan and Malaysia, 2018
National Natural Science Fund for Distinguished Young Scholars of China, 2017
WuXi AppTec Scholar Award in Life Science and Chemistry, 2016
Distinguished Junior Faculty Award by Chinese-American Chemistry & Chemical Biology
Professor Association (CAPA), 2014
Amgen Young Investigator Award, 2013
Thieme Chemistry Journal Award, 2011
National Science Foundation (NSF) CAREER Award, 2011
Professional memberships
Associate Editor, Organic Letters, 2023 – present
Member of American Chemical Society, 1999 – present
Member of Chinese Chemical Society, 2015 – present
Faculty 1000, 2013 – present
Selected publications
Researcher ID: A-8063-2013, ORCID: 0000-0002-5067-9889
1. Palladium-Catalyzed C−H Glycosylation for Synthesis of C-Aryl Glycosides Quanquan Wang, Shuang An, Zhiqiang Deng, Wanjun Zhu, Zeyi Huang, Gang He*, and Gong Chen* Nature Catal., 2019, 2, 793-800.
2. Epimerization of Tertiary Carbon Centers via Reversible Radical Cleavage of Unactivated C(sp3)-H Bonds Yaxin Wang+, Xiafei Hu+, Cristian A. Morales-Rivera, Guo-Xing Li, Xin Huang, Gang He*, Peng Liu*, and Gong Chen* J. Am. Chem. Soc., 2018, 140, 9678-9684.
3. Palladium-Catalyzed Amide-Directed Enantioselective Hydrocarbofunctionalization of Unactivated Alkenes Using a Chiral Monodentate Oxazoline Ligand. Hao Wang, Zibo Bai, Tangqian Jiao, Zhiqiang Deng, Huarong Tong, Gang He*, Qian Peng*, and Gong Chen* J. Am. Chem. Soc. 2018, 140, 3542-3546.
4. A General Strategy for Synthesis of Cyclophane-Braced Peptide Macrocycles via Palladium-Catalyzed Intramolecular sp3 C−H Arylation. Xuekai Zhang, Gang Lu, Meng Sun, Madhu Mahankali, Yanfei Ma, Mingming Zhang, Wangde Hua, Yuting Hu, Qingbing Wang, Jinghuo Chen, Gang He*, Xiangbing Qi*, Weijun Shen*, Peng Liu* and Gong Chen*. Nature Chem. 2018, online. doi:10.1038/s41557-018-0006-y
5. An Enantioselective Bidentate Auxiliary Directed Palladium- Catalyzed Benzylic C H Arylation of Amines Using a BINOL Phosphate Ligand. Hao Wang, Hua-Rong Tong, Gang He*, and Gong Chen*. Angew. Chem., Int. Ed. 2016, 55, 15387-15391.
6. Benzazetidine Synthesis via Palladium-Catalyzed Intramolecular C−H Amination. Gang He,* Gang Lu, Zhengwei Guo, Peng Liu,* and Gong Chen*. Nature Chem. 2016, 8, 1131-1136.
7 Total Synthesis of Mannopeptimycins and α and β. Bo Wang, Yunpeng Liu, Rui Jiao, Yiqing Feng, Qiong Li, Chen Chen, Long Liu, Gang He, and Gong Chen*. J. Am. Chem. Soc. 2016, 138, 3926-3932, DOI: 10.1021/jacs.6b01384
8. Pd-catalyzed Mono-selective ortho-C−H Alkylation of N-Quinolyl Benzamides: Evidence for Stereo-retentive Coupling of Secondary Alkyl Iodides. Shuyu Zhang, Qiong Li, Gang He, William A. Nack, and Gong Chen*. J. Am. Chem. Soc. 2015, 137, 531-539.
9. Stereoselective Synthesis of β-Alkylated α-Amino Acids via Palladium-Catalyzed Alkylation of Methylene C(sp3)−H Bonds. Shu-Yu Zhang, Qiong Li, Gang He, William A. Nack, and Gong Chen*. J. Am. Chem. Soc. 2013, 135, 12135−12141.
10. Use of a Readily Removable Auxiliary Group for the Synthesis of Pyrrolidones by the Palladium-Catalyzed Intramolecular Amination of Unactivated C(sp3)−H Bonds. Gang He, Shu-Yu Zhang, William A. Nack, and Gong Chen*. Angew. Chem., Int. Ed. 2013, 52, 11124−11128.
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