Gong Chen Lab @ Nankai / 南开大学陈弓课题组

Prof. Gong Chen (陈弓)

E-mail: gongchen@nankai.edu.cn


Education

1998     BS, Nanjing University, China 2004     PhD, Columbia University, USA

Academic career

2015-present  Professor, State Key Laboratory of Elemento-organic Chemistry, Nankai University, China

2018-present  Adjunct professor, The Pennsylvania State University, USA

2014-2015      Associate Professor, Department of Chemistry, The Pennsylvania State University

2008-2014      Assistant Professor, Department of Chemistry, The Pennsylvania State University, USA

2005-2008      Postdoctoral fellow, Memorial Sloan-Kettering Cancer Center, USA

Honors

ACP lectureship awards in Japan and Malaysia, 2018
Tianjin Young Science and Technology Innovation Leader, 2017
National Natural Science Fund for Distinguished Young Scholars of China, 2017
WuXi AppTec Scholar Award in Life Science and Chemistry, 2016
Young Chang Jiang Scholar (MOE China), 2015
Distinguished Junior Faculty Award by Chinese-American Chemistry & Chemical Biology
Professor Association (CAPA), 2014
Amgen Young Investigator Award, 2013
Thieme Chemistry Journal Award, 2011
National Science Foundation (NSF) CAREER Award, 2011
Penn State Clinical and Translational Science Award (CTSA), 2009
New York State Breast Cancer Research Postdoctoral Fellowship, 2007

Professional memberships

Member of American Chemical Society 1999 – present
Member of Chinese Chemical Society 2015 – present
Faculty 1000 2013 – present

Selected publications
Researcher ID: A-8063-2013, ORCID: 0000-0002-5067-9889

1. Palladium-Catalyzed Amide-Directed Enantioselective Hydrocarbofunctionalization of Unactivated Alkenes Using a Chiral Monodentate Oxazoline Ligand. Hao Wang, Zibo Bai, Tangqian Jiao, Zhiqiang Deng, Huarong Tong, Gang He*, Qian Peng*, and Gong Chen* J. Am. Chem. Soc. 2018, 140, 3542-3546. DOI: 10.1021/jacs.8b00641.

2. A General Strategy for Synthesis of Cyclophane-Braced Peptide Macrocycles via Palladium-Catalyzed Intramolecular sp3 C−H Arylation. Xuekai Zhang, Gang Lu, Meng Sun, Madhu Mahankali, Yanfei Ma, Mingming Zhang, Wangde Hua, Yuting Hu, Qingbing Wang, Jinghuo Chen, Gang He*, Xiangbing Qi*, Weijun Shen*, Peng Liu* and Gong Chen*. Nature Chem. 2018, online. doi:10.1038/s41557-018-0006-y

3. An Enantioselective Bidentate Auxiliary Directed Palladium- Catalyzed Benzylic C H Arylation of Amines Using a BINOL Phosphate Ligand. Hao Wang, Hua-Rong Tong, Gang He*, and Gong Chen*. Angew. Chem., Int. Ed. 2016, 55, 15387-15391.

4. Benzazetidine Synthesis via Palladium-Catalyzed Intramolecular C−H Amination. Gang He,* Gang Lu, Zhengwei Guo, Peng Liu,* and Gong Chen*. Nature Chem. 2016, 8, 1131-1136.

5. Total Synthesis of Mannopeptimycins and α and β. Bo Wang, Yunpeng Liu, Rui Jiao, Yiqing Feng, Qiong Li, Chen Chen, Long Liu, Gang He, and Gong Chen*. J. Am. Chem. Soc. 2016, 138, 3926-3932, DOI: 10.1021/jacs.6b01384

6. Pd-catalyzed Mono-selective ortho-C−H Alkylation of N-Quinolyl Benzamides: Evidence for Stereo-retentive Coupling of Secondary Alkyl Iodides. Shuyu Zhang, Qiong Li, Gang He, William A. Nack, and Gong Chen*. J. Am. Chem. Soc. 2015, 137, 531-539.

7. Stereoselective Synthesis of β-Alkylated α-Amino Acids via Palladium-Catalyzed Alkylation of Methylene C(sp3)−H Bonds. Shu-Yu Zhang, Qiong Li, Gang He, William A. Nack, and Gong Chen*. J. Am. Chem. Soc. 2013, 135, 12135−12141.

8. Use of a Readily Removable Auxiliary Group for the Synthesis of Pyrrolidones by the Palladium-Catalyzed Intramolecular Amination of Unactivated C(sp3)−H Bonds. Gang He, Shu-Yu Zhang, William A. Nack, and Gong Chen*. Angew. Chem., Int. Ed. 2013, 52, 11124−11128.

9. Palladium-Catalyzed Picolinamide-Directed Alkylation of Unactivated C(sp3)−H Bonds with Alkyl Iodides. Shuyu Zhang, Gang He, William A. Nack, Yingsheng Zhao, Qiong Li, and Gong Chen* J. Am. Chem. Soc. 2013, 135, 2124−2127.

10. Efficient Ether Synthesis via Palladium-catalyzed Picolinamide-directed Alkoxylation of Unactivated C(sp3) and C(sp2)−H Bonds at Remote Positions. Shuyu Zhang, Gang He, Yingsheng Zhao, and Gong Chen* J. Am. Chem. Soc. 2012, 134, 7313−7316.